Blade is back, and he's hunting a new threat: the Tryk, an extremely vicious mutant vampire species. Complicating the situation is the appearance of the Seven, a secret society dedicated to the destruction of supernatural evil. Incredibly, they see Blade as the most dangerous vampire of all! And at the same time, an ancient vampiric text sends Blade on a quest to renounce his monstrous heritage and become fully human at last. But can a mere human withstand the murderous Tryk?